Increased sodium transport by cortical collecting tubules from remnant kidneys
نویسندگان
چکیده
منابع مشابه
Osmosis in Cortical Collecting Tubules
This paper reports a theoretical analysis of osmotic transients and an experimental evaluation both of rapid time resolution of lumen to bath osmosis and of bidirectional steady-state osmosis in isolated rabbit cortical collecting tubules exposed to antidiuretic hormone (ADH). For the case of a membrane in series with unstirred layers, there may be considerable differences between initial and s...
متن کاملThe single nephron preparation--cortical collecting tubules.
As Dr. Burg has pointed out, the rabbit has practically the only kidney fromi which nephrons can be dissected conveniently. We have dissected collecting tubules from human kidneys recently, but dissection of the rabbit kidney is far easier and the supply of kidneys certainly more dependable. Two points about the renal anatomy in the rabbit need to be emphasized. First of all, the cortical colle...
متن کاملBicarbonate secretion by rabbit cortical collecting tubules in vitro.
We previously reported that rabbit renal cortical collecting tubules can secrete bicarbonate in vitro (i.e., there can be net transport from bath to lumen, causing the concentration in the lumen to increase). Net bicarbonate secretion was observed most often when rabbits had been pretreated with NaHCO(3) and were excreting alkaline urine before being killed for experiments. The purpose of the p...
متن کاملPrenatal programming of rat cortical collecting tubule sodium transport.
Prenatal insults have been shown to lead to elevated blood pressure in offspring when they are studied as adults. Prenatal administration of dexamethasone and dietary protein deprivation have demonstrated that there is an increase in transporter abundance for a number of nephron segments but not the subunits of the epithelial sodium channel (ENaC) in the cortical collecting duct. Recent studies...
متن کاملShort-term effects of uninephrectomy on electrical properties of the cortical collecting duct from rabbit remnant kidneys.
Microelectrode techniques were used to assess the electrical properties of the collecting duct cell in the isolated perfused cortical collecting duct from remnant kidneys 3, 6, and 24 h after uninephrectomy (UNX); results were compared with those from sham-operated kidneys. Plasma aldosterone levels did not change during the time course after UNX. The lumen-negative transepithelial voltage was ...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1989
ISSN: 0085-2538
DOI: 10.1038/ki.1989.165